Acute-onset postoperative endophthalmitis caused by multidrug-resistant Klebsiella pneumoniae

نویسندگان

  • Shekhar Sanghi
  • Avinash Pathengay
  • Animesh Jindal
  • Vishal Raval
  • Sameera Nayak
  • Savitri Sharma
  • Abhishek Bawdekar
  • Harry W Flynn
چکیده

The purpose of this paper is to report outcomes of intravitreal imipenem in the treatment of multidrug-resistant Klebsiella-related postoperative endophthalmitis. This observational case series consists of three eyes from three patients seen between 2013 and 2014. Multidrug-resistant Klebsiella pneumoniae is characterized by a rapid, fulminant course and severe intraocular inflammation. Intravitreal imipenem may be used to treat such infection.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multidrug Resistance in Infants and Children

Bacterial infections may cause disease and death. Infants and children are often subject to bacterial infections. Antimicrobials kill bacteria protecting the infected patients andreducing the risk of morbidity and mortality caused by bacteria. The antibiotics may lose their antibacterial activity when they become resistant to a bacteria. The resistance to different antibiotics in a bacteria is ...

متن کامل

Anti-biofilm Effects of Zinc Oxide Nanoparticles Synthesized by Leaf Extract of Typha Latifolia on Biofilm Gene Expression in Multidrug-Resistant Klebsiella Pneumoniae Strains: A Laboratory Study

Background and Objectives: Biofilms are a community of bacteria on surfaces coated with extracellular polymeric materials, and one strategy to remove biofilms is to use nanoparticles. The aim of this study was to synthesize green zinc oxide (ZnO) nanoparticles and determine its anti-biofilm effects on biofilm gene expression in multidrug-resistant Klebsiella pneumoniae strains. Materials and M...

متن کامل

Synergistic effect of Thymbra spicata L. extracts with antibiotics against multidrug- resistant Staphylococcus aureus and Klebsiella pneumoniae strains

Objective(s): To evaluate the in vitro interaction between different extracts of Thymbra spicata L. and certain antimicrobial drugs of different mechanisms, including ampicillin, cefotaxime, amikacin and ciprofloxacin. This study was performed against multidrug-resistant strains of Staphylococcus aureus and Klebsiella pneumoniae. Materials and Methods: Evaluation of antibacterial activity and ...

متن کامل

شناسایی ایزوله ‌های کلبسیلا پنومونیه دارای ژن blaCTX و تعیین مقاومت متقاطع آنها در بیماران بستری در بیمارستان

Background and Aim: Klebsiella pneumoniae is a member of the Enterobacteriaceae family. There is a global emergence of multidrug-resistant (MDR) strains of K. pneumoniae, a Gram-negative enteric bacterium that causes nosocomial and urinary tract infections. The aims of the present study were to identify the Klebsiella pneumoniae infections in hospitalized patients, characterization of blaCTX ge...

متن کامل

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae strains into opportunistic, hypervirulent, and multidrug-resistant groups and separates K. pneumoniae from two closely related species, Klebsiella variicola and Klebsiella quasipneumoniae. Some strains of K. pneumoniae act as oppo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2014